Types of Addiction

1 in 4 Adults in England Could Be Hooked On Prescribed Drugs

Last updated:
June 23, 2025

A new report commissioned by the government to review addictive prescription drugs has revealed that 1 in 4 adults was prescribed them last year.

Public Health England (PHE) took information from prescribing data, literature and personal experiences to review 5 specific classes of prescribed drugs. These classes of drugs are associated with drug abuse, dependence and addiction.

Person pouring white pills from orange prescription bottle into their palm

The government requested the report in light of the fact that the current guidelines and controls in place for these classes of medications have had little impact.

Britain is in the midst of an opioid crisis with opiate-related deaths soaring to shocking levels in recent years. The concern is that overprescribing is fuelling the current public health crisis.

The top most addictive prescription drugs available

The government instructed Public Health England to review the following five classes of medications, all of which are potentially addictive, can have serious side effects and withdrawal symptoms. They are also medicines that have been linked to many deaths:

  • Antidepressants
  • Benzodiazepines
  • Opioid pain killers (for non-cancer-related pain such as injury-related or degenerative joint disease)
  • Gabapentanoids
  • Z-drugs (Z-drugs are a class of drugs that have similar effects to benzodiazepines and are used in the treatment of insomnia. Hypnotic sedatives such as Zopiclone and Zolpidem are examples of the Z- drugs)

Whilst antidepressants are not necessarily considered addictive drugs in the same way as the other classes of reviewed medications, and they are often co-prescribed. Many antidepressants are difficult to withdraw from, and certain types of antidepressants have sedative effects and can, therefore, be abused for these effects.

Current prescribing guidelines deemed ineffective

Whilst tighter controls are now in place for these classes of prescription drugs, and it is evident from the latest statistics that guidelines are not as effective as they need to be.

Public Health England’s findings were published in a report released to press on the 10th September 2019. The report identifies the following key points:

  • Long term prescribing of opioid pain medicines and benzodiazepines has fallen. However, it still occurs far too frequently and is not in line with the current prescribing guidelines
  • 1 in 4 adults have been prescribed at least one of these classes of medicines during the year March 2017/18
  • In March 2018, half of those being prescribed at least one of these classes of prescription drugs had been continuously prescribed it for at least the preceding 12 months.
  • Between 22 and 32% had received a prescription for one of these classes of prescription drugs for at least the previous 3 years

Prescribing guidelines state opiates and opioids should not be prescribed for any longer than 3 months for non-cancer-related conditions and benzodiazepines for no longer than 28 days.

Patients interviewed for the report felt they were not given enough information regarding the addictiveness of these drugs and the dangers associated with them at the time of prescribing. 

England’s gabapentinoid and antidepressant prescriptions continue to rise

The report found that whilst prescriptions for opioids, benzos and Z-drugs are falling, gabapentinoid and antidepressant prescriptions are rising.

Females and older adults (in particular those aged 75 and over) are prescribed the most from the reviewed classes of medications. This suggests that GPs view the older generation differently, when, in fact, they are the most vulnerable.

The fact that gabapentinoid prescriptions are continuing to rise is very concerning. Whilst gabapentinoid medications such as pregabalin and gabapentin are very effective in treating pain, in particular, neuropathic pain, they are very addictive and can easily be abused. When taken over a prolonged period of time, they also cause drug dependence.

Pregabalin is now often prescribed as an anti-anxiety drug to treat anxiety-related disorders.

Graph showing increasing deaths related to pregabalin and gabapentin in England from 2007 to 2017, highlighting the dangers of prescribed drug misuse

Pregabalin and gabapentin related deaths have soared along with prescriptions

Both Pregabalin and gabapentin have euphoric and sedative effects when abused. When mixed with alcohol, another sedative or opiate, they become dangerously unpredictable.

Higher prescribing rates linked to deprivation

PHE’s report evidenced a strong link between higher prescribing rates and deprivation. The report also evidenced a clear North/South divide when it comes to prescribing of the reviewed classes of addictive drugs in England. Similarly, drug overdoses and drug-related deaths are much higher in the North of England than they are in the South.

Bar chart showing age-standardised mortality rates for drug misuse deaths across regions of England and Wales in 2018, highlighting higher rates in northern regions

Drug deaths are double in the North of England where there is more deprivation

Higher prescribing rates and deprivation were linked by the following key findings:

Prescribing rates and prescription duration are much higher in some of England’s most deprived areas

  • Prescribing rates for opioids and gabapentinoids are 1.6 times higher in England’s most deprived areas than they are in the least deprived areas
  • Co-prescribed medicine rates (where two or more of the reviewed classes of medicines are prescribed) are also higher in England’s more deprived cities

Help for prescription drug dependence and prescription drug addiction

According to Public Health England’s report, there could potentially be millions of people in the UK suffering from prescription drug dependence or addiction. In response to their findings, PHE has demanded that the government set up a helpline. However, will this really be enough?

Most individuals suffering from drug dependence, whether it is to prescription drugs or illicit drugs, require professional medical and therapeutic help in order to come off the drugs safely and to stay off them long term.

If you or a loved one are suffering from prescription drug dependence, please DO NOT stop taking your medication suddenly. Acute withdrawal symptoms from these drugs can be life-threatening.

Detox Plus UK specialises in professional private drug detox and drug rehab for all manner of prescription drugs and illicit drugs. We can facilitate a full medical detox to ensure that your wellbeing is not put at risk whilst you stop the medication.

All of our detoxes and treatment programmes are tailored specifically to the individual. With high levels of medical and therapeutic support, you will be able to stop your medication successfully and comfortably.

Call us today on 02072052734 or complete the enquiry form to find out more about how we can help you or your loved one to break free from prescription drug addiction and dependence.

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